A Manual of Materia Medica
and Pharmacology
by David M. R. Culbreth, Ph.G., M.D. (1927)
Zingiber
ZINGIBER. GINGER, U.S.P.
Zingiber officinale, Roscoe.
The dried rhizome, with outer cortical layers often partially or completely
removed, yielding not less than 2 p.c. non-volatile ether-soluble extractive
nor 12 p.c. cold water extractive.
Habitat. India, Hindustan (cultivated
in W. Indies, Africa).
Syn. Zingib, Jamaica, Black, African
or Race Ginger; Fr. Gingembre (gris et blanc); Ger. Rhisoma (Radix)
Zingiberia, Ingwer.
Zin'gi'ber. L. fr. Skt. Gringavera
-- gringa, horn, + vera, body, horn-shaped -- i.e., shape of roots;
Ar., Pers. zanjabil zenjebil; Eng. ginger.
Of-fi-ci-na'le. L. officina,
workshop; opus, work, + facere, to do -- i.e., used in the shop or
store.
PLANT. -- Perennial herb; stem barren, leafy, 1-1.3
M. (3-4 degrees) high, entirely covered with the leaf-sheaths, solid; round:
leaves 15-30 Cm. (6-12') long, 2.5-4 Cm. (1-1 3/5') wide; flowering stalk
from stem 15-30 Cm. 6-12') long, terminating in a spike; flowers dingy
yellow, 2-3 at a time. RHIZOME: Jamaica, horizontal, cork wholly
removed, laterally compressed, irregularly branched, 4-16 Cm. (1 3/5-6/2/5')
long, 4-20 Mm. (1/6-4/5') thick, light brown, longitudinally striate, ends
of branches with depressed stem-scars; fracture short-fibrous; starchy,
resinous; internally yellowish, light brown; odor agreeably aromatic; taste
aromatic, pungent; Cochin, most of corky layer removed on flattened sides,
light brown, grayish-yellow; fracture shorter, less fibrous more starchy
than other varieties; internally yellowish-white, oil and resin cells,
yellowish, brownish-red; odor aromatic: taste pungent; African, cork partly
removed on flattened sides, areas without cork smooth, light brown, portions
with cork longitudinally or reticulately wrinkled and grayish-brown; fracture
short-fibrous; internally light yellow, brown; odor strongly aromatic;
taste aromatic, strongly pungent, otherwise resembling Jamaica. POWDER,
light yellow (Jamaica), light brown (Cochin), light brown, (African) --
numerous starch grains .005-.04 Mm. (1/5000-1/625') broad, nearly spherical,
ovoid, elliptical, pyriform, hilum excentric near smaller end, fibers long,
non-lignified, oblique pores, occasional cells with brownish resin-like
contents; tracheae; yellowish, brownish cork cells, thin-walled, occasional
in Jamaica, fairly numerous in Cochin and African. Solvents: alcohol;
acetone; ether; boiling water partially. Dose, gr. 5-20 (.3-1.3 Gm.).
ADULTERATIONS. -- RHIZOME: Fibrous, light, friable,
worm-eaten pieces (all discarded); POWDER: Rice Starch, flour, curcuma,
brick-dust, chalk, capsicum, mustard (detected by microscope, iodine T.S.,
ash), "spent ginger" -- that partially or wholly exhausted.
Commercial. -- Plant reed-like, is propagated
by rhizome segments, thrives best on new forest soil, and yields when one
or more years old (the younger the better) very acceptable rhizomes, which
are dug after the stems have withered, Jan.-Feb., cleaned carefully to
avoid bruising, hence discoloration, washed in boiling water to hydrate
starch and prevent germination, and then rapidly dried, constituting as
such black, coated, unpeeled, unscraped ginger, in contradistinction to
the further prepared white, uncoated, peeled, scraped, race, hand ginger--the
former, owing to most oil and resin residing in the periderm, being richer
and stronger. May bleach artificially by sulphur fumes (SO2),
chlorinated lime (Cl), milk of lime, or gypsum. There are several
varieties, three being given pharmacopoeial prominence: 1, Jamaica, sometimes
steeped in milk of lime, and covered with calcium carbonate, thereby preventing
insect attack; least pungent, most delicate and handsome; reaches us via
England, or direct from W. Indies; 2,Cochin (Chinese), resembles somewhat
the Jamaica, but seldom enters our market commercially; 3, African, generally
recognized as possessing greater pungency but less acceptable aroma than
the preceding, with shorter rhizome and broadly linear or oblong lobes;
yields 8-10 p.c. of oleoresin; 4, Calcutta (E. India), resembles closely
the African; reaches us via Calcutta; yields 8 p.c. of oleoresin; 5, Calcut
(E. India), resembles closely the African; reaches us from Calicut; yields
8 p.c. of oleoresin; 6, Japanese, resembles closely the Cochin, and seldom
becomes a commercial article with us. The green (lobed branches recently
dug and marketed without drying), and preserved (fresh rhizome steeped
in hot syrup, becoming soft, brownish, translucent, efflrescent) are popular
trade forms.
CONSTITUENTS. -- Volatile oil 1-3 p.c., Gingerol
.5-1.5 p.c., Resin (2), starch 20 p.c., mucilage, ash 4-8 p.c.
Volatile Oil. -- Mostly phellandrene, C15H24,
and d-camphene C10H16; thickish, greenish-yellow; sp. gr. 0.885; gives
aromatic odor and flavor, but not the pungency.
Gingerol. -- Not a glucoside, but a straw-colored,
viscid, inodorous, non-volatile, pungent liquid, imparting the hot taste;
soluble in fat, benzene, carbon disulphide, volatile oils, alcohol, ether.
PREPARATIONS. -- Fluidextractum Zingiberis.
Fluidextract of Ginger. (Syn., Fldext. Zingib., Fluid Extract of
Ginger; Fr. Extrait fluide de Gingembre; Ger. Ingwerfluidextrakt.)
Manufacture: Similar to Fluidextractum Sarsaparillae,
page 126; menstruum: alcohol. Dose, mv-20 (.3-1.3 cc.).
Preps.: 1. Syrupus Zingiberis. Syrup of Ginger.
(Syn., Syr. Zingib.; Fr. Sirop de Gingembre; Ger. Ingwersirup.)
Manufacture: 3 p.c. Mix fluidextract
of ginger 3 cc. and alcohol 2, triturate liquid with magnesium carbonate
1 Gm., sucrose 6, gradually add, constantly triturating, water 43 cc.,
filter, dissolve in clear filtrate, gently heating, sucrose 76 Gm., strain
syrup (hot), when cold add through strainer water q.s. 100 cc. Dose,
3ss-2 (2-8 cc.).
2. Elixir Hydrastis Compositum, N.F., .875
p.c.
2. Tinctura Zingiberis. Tincture of
Ginger. (Syn., Tr. Zingib., Tincture of Jamaica Ginger; Fr.
Teinture de Gingembre; Ger. Ingwertinktur.)
Manufacture: 20 p.c. Similar to Tinctura
Veratri Viridis, page 104; menstruum: 85 p.c. alcohol. Impurities:
Capsicum, similar pungent substitutes. Dose, mxx-60 (1.3-4 cc.).
Prep.: 1. Acidum Sulphuricum Aromaticum,
5 p.c.
3. Pulvis Rhei Compositus, 10 p.c.
4. Pulvis Aromaticus, N.F., 35 p.c. 5. Pulvis Aromaticus
Rubefaciens, N.F., 20 p.c. 6. Pulvis Myricae Compositus, N.F.,
30 p.c. 7. Tinctura Antiperiodica, N.F., 1/13 p.c. 8.
Tinctura Aromatica N.F., 4 p.c.
Unoff. Preps.: Infusion, 5 p.c., 3j-2 (30-60
cc.). Oleoresin (ether) -- yield 5-10 p.c., mss-2 (.03-.13 cc.).
PROPERTIES. -- Like other aromatics, carminative,
stimulant, sternutatory, rubefacient, anodyne, sialagogue. This was
introduced from Asia, through Arabia into Greece and Europe. The
Arabian and Greek physicians used it as a condiment, carminative, stimulant,
aphrodisiac.
USES. -- Atonic dyspepsia, flatulent colic, atonic
gout, diarrhea, cholera, chronic bronchitis, alcoholic gastritis, corrective
to nauseous medicines. Externally -- colic, rheumatism, neuralgia,
toothache, headache; in cataplasms, fomentations. The infusion for
relaxed uvula, masticated for paralysis of tongue. Zingiber Zerum'bet,
Java (rhizome fleshy, spongy, ginger odor and taste), and Z. cassumu'nar,
India (root 5 Cm. (2') long, fleshy radicles, white tubers, scaly, brown;
odor and taste camphoraceous) -- both used in their respective countries.
Z. Mio'ga, cultivated in China, Japan -- bergamot taste, slightly
pungent.
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