A Manual of Materia Medica
and Pharmacology
by David M. R. Culbreth, Ph.G., M.D. (1927)
Xanthium
Xan'thium Struma'rium, Broad Cocklebur; N.
America. Achenes 2.5 Cm. (1') long, flat, oblong, without pappus,
enclosed in the involucre, which is densely beset with hooked prickles.
X. spino'sum, Spiny or Thorny Clotbur; N. America, S. Europe; leaves with
spines at base 2.5 Cm. (1') long; fertile axillary burs (achenes) crowned
with 1 inconspicuous beak. X canaden'se, and its var. echina'tum;
achenes, with 2 stout beaks, hooked, 2.5 Cm. (1') long, densely prickly,
hispid; river banks, waste places; var. echinatum, smaller plant -- possibly
unworthy of variety distinction.
Xanthorrhiza
Xanthorrhi'za apiifo'lia, Shrub Yellow-Root. --
The rhizome and roots, U.S.P. 1820-1870; S. and C. United States.
Shrub .6-1 M. (2-3 degrees) high, stem clustered, 6 Mm. (1/4') thick, wood
yellow, leaves compound, flowers April, purple, racemes, rhizome .6-1 M.
(2-3 degrees) long, 12 Mm. (1/2') thick, yellowish internally and externally,
bitter; contains berberine, resin, starch, gum, etc. Used as a tonic
like calumba or quassia; in infusion, decoction, tincture. Dose,
3ss-1 (2-4 Gm.).
Xanthoxylum
Zanthox'ylum america'num and Z. Cla'va-Her'culis.
1. Xanthoxylum, Prickly Ash Bark, N.F. -- The dried bark with
not more than 2 p.c. of foreign organic matter; 2. Xanthoxyli Fructus,
Prickly Ash Berry, N.F. The dried fully grown fruit with not
more than 2 p.c. of foreign organic matter; N. America; Z. americanum,
Canada to Virginia -- Northern; Z. Clava-Herculis, Virginia to Florida
-- Southern. Z. americanum, shrub 2-4 M. (6-12 degrees) high, covered
with sharp, scattered prickles; leaves imparipinnate, leaflets 4-5 pairs;
flowers before the leaves, yellowish-green, corolla absent. Bark,
transversely curved fragments, quills, 2-15 Cm. (4/5-6') long, bark .5-2
Mm. (1/60-1/12') thick, light gray, with foliaceous lichens, wrinkled,
whitish lenticels, fewe straight, 2-edged spines linear at base, 5 Mm.
(1/5') high, numerous shining crystals, fracture short, uneven, odor slight;
taste bitter, acrid, pungent. Powder, light grayish-brown -- parenchyma
with starch grains, oily globules, calcium oxalate prisms; Northern --
only a few non-lignified bast-fibers, stone cells and cork cell fragments;
Z. Clava-Herculis, small tree, 6-12 M. (20-40 degrees) high, .3-.6
M. (1-2 degrees) thick, with prickles protruding through large corky cones,
larger prickles on branches and petioles; leaflets 3-8 pairs, crenate;
flowers after leaves appear, corolla present. Bark, transversely
curved, irregular, oblong, flattened pieces, quills 2-40 Cm. (4/5-16')
long, bark 1-4 Mm. (1/25-1/6;) thick, light gray, with numerous large barnacle-shaped
projections of cork, .5-3.5 Cm. (1/5-1/2/5') thick, often 2 Cm. (4/5')
high, lenticels, foliaceous lichens, obscurely striate, without crystals;
odor and taste as in preceding. Fruit, capsules with short stalks
(Z. americanum) or without stalks (Z. Clava-Herculis), ellipsoidal,
fleshy, gray-brown, dehiscent; seeds 1-2 oblong, black; odor faintly aromatic,
citral-like; taste of two species quite different, but both pungent, warm
aromatic, tingling sensation on chewing. Powder, dark brown -- pericarp
tissue with oil cavities, parenchyma cells with spherocrystals of hesperidin,
numerous globules of volatile oil; solvents: alcohol, boiling water; contain
(root and fruit) resins (2), alkaloid (bitter--berberine (?)), xanthoxylin
(tasteless, inert, crystalline), volatile oil (acrid, green), tannin, sugar,
fat, gum, ash 12 p.c. Alterative, stimulant, sialagogue, diaphoretic,
diuretic--causes salivation, tingling in tongue, increased cardiac action
and arterial tension, also secretion from stomach intestines, liver, and
pancreas; resembles mezereum, guaiac, sanguinaria and stillingia in action;
chronic rheumatism, myalgia, lumbago, dropsies, atonic dyspepsia, diarrhea,
syphilis, pharyngitis--masticatory for toothache, paralysis of tongue;
externally: counter-irritant in female pelvic diseases. Dose, gr.
15-30 (1-2 Gm.); Root: 1. Fluidextractum Xanthoxyli (75 p.c.
alcohol), dose, mxv-30 (1-2 cc.): Preps.: 1. Elixir Corydalis Compositum,
3 p.c.; 2. Elixir Hydrastis Compositum, 1.75 p.c. Decoction,
5 p.c., 3ss-2 (15-60 cc.), Extract, gr. 3-10 (.2-.6 Gm.); Fruit (berry):
1. Fluidextractum Stillingiae Compositum, 6.2 p.c.: Prep.: 1. Syrupus
Stillingiae Compositus. Z. florid'anum, Satin Wood, identical
with Z. carib'aenum; Z. ptero'ta, Florida, Texas, Brazil -- wood
yellow, hard, bark and leaves pungent.
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