A Manual of Materia Medica
and Pharmacology
by David M. R. Culbreth, Ph.G., M.D. (1927)
Galega
Gale'ga officina'lis, Galega, European Goat's
Rue, N.F. -- The dried flowering herb with no stems over 4 Mm. (1/6')
thick or more than 3 p.c. of foreign organic matter; S. Europe. Small
perennial; stem smooth, 15-45 Cm. (6-18') long, usually cut and broken;
leaves imparipinnate, leaflets bright green, lanceolate, 2-5 Cm. (4/5-2')
long, 2-6 Mm. (1/12-1/4') broad; flowers white, violet, racemes; odor indictinct;
taste mucilaginous, slightly bitter, astringent -- colors saliva yellowish-green.
Powder, yellowish-green -- stomata, non-glandular hairs, tracheae, crystal-fibers
with calcium oxalate monoclinic prisms, isodiametric parenchyma, pollen
grains, few or no starch grains; solvent: diluted alcohol; contains bitter
principle, tannin, ash 12 p.c. , diuretic, diaphoretic, vermifuge.
Dose, 3ss-1 (2-4 Gm.); 1. Fluidextractum Galegae (diluted alcohol).
Garcinia
CAMBOGIA. GAMBOGE, U.S.P.
Garcinia Hanburyi, Hooker filius.
The gum-resin with not more than 1 p.c. foreign organic matter, yielding
not more than 1 p.c. acid-insoluble ash, nor less than 65 p.c. alcohol-soluble
extractive.
Habitat. Annam, Camboja (Cambodia),
Siam, Cochin-China.
Syn. Cambog., Pipe Gamboge, Gummi-resina
Guttae (Gutti), Gutta Gamba, Cambodia; Fr. Gomme-gutte; Ger. Gutti,
Gummigutt.
Gar-cin'i-a. L. named after Laurent
Garcin, French botanist and oriental traveler, who first described
it in 1734.
Han-bu'ry-i. L., in memory of Daniel
Hanbury, named by Sir Joseph Dalton Hooker.
Cam-bo'gi-a. L. usually called Cambodia,
a French protectorate in farther India, where it is indigenous.
Gamboge. The trade name, corruption
of Camboge.
PLANT. -- A tree 10.5-15 M. (35-50 degrees) high,
with many spreading branches; bark orange-brown, thick; leaves 10-17.5
Cm. (4-7') long, laurel-like; flowers Feb., dioecious, small, yellow, in
4's, staminate ones on pedicels (pedicula'ta) 6 Mm. (1/4') long; fruit
may-June, size of crab apple, 3 Cm. (1 1/5') in diameter; smooth, orange-green
color, with 4 dissepiments, each having 1 seed 12-18 Mm. (1/2-3/4') long.
GUM-RESIN (gamboge), in hard, brittle, cylindrical pieces, usually hollow
in center, 10-20 Cm. (4-8') long, 2-5 Cm. (4/5-2') thick, grayish-orange-brown,
longitudinally striate; fracture brittle, conchoidal, smooth, dull orange-red
surface; odorless; taste acrid. POWDER, bright yellow -- few or no
starch grains; mounted in chloral hydrate T.S. all particles slowly dissolve
leaving a few scattered fragments of vegetable tissues. Tests: 1.
Dissolve completely by successive treatments of ether or alcohol, and water.
2. Rub with water -- yellow emulsion, darker and almost transparent upon
adding ammonia T.S.; + iodine T.S. -- not green (abs of starch); not more
than 35 p.c. should be insoluble in alcohol. Solvents: alcohol or
ether dissolves at least 65 p.c. Dose, gr. 1/2-5 (.03-.3 Gm.).
ADULTERATIONS. -- Wheat and rice flour, sand, stones,
nails, spikes, powdered wood or bark -- mostly in the cake variety, giving
greater hardnesss and coarser fracture; when many fragments of rice paper
present -- "ricey."
Commercial. -- Gamboge secretes in latex-tubes
(ducts) in the middle bark and to some extent in the pith, alburnum, leaves,
flowers, and fruit; it is at first a yellow milky juice obtained in drops
from broken leaves, twigs, or artificial incisions, being caught in leaves,
cocoanut shells or bamboo joints. There are two varieties: 1, Pipe
(Roll, Fine), the best, resulting from making, at the beginning of the
rainy season, June-Oct., a spiral incision in the bark half around the
tree trunk from the ground upward a number of feet, and collecting the
slowly exuding juice in a hollow bamboo joint placed at the lower end of
the incision, requiring 1-2 months to fill and harden, in which the contraction
toward the sides often affords a central cylindrical cavity; upon cracking
off the bamboo shell, that usually imparts its markings, the contents are
ready for market; trees should only be tapped biennially and each should
yield 3 bamboo joints 50 Cm. (20') long, 4 Cm. (1 3/5') thick; 2, Cake
(Lump, Saigon, Cochin, Coarse), inferior, resulting from collecting the
juice in leaves and various vessels, being subjected to exposure and adulteration,
thereby becoming less uniform and brittle with dull brownish non-conchoidal
fracture; usually in masses, 2-3 pounds (.7-1 Kg.), sometimes much larger,
being pressed or run into boxes or tubs. Enters market via Canton,
Calcutta, Singapore, Saigon, Bangkok, etc.
CONSTITUENTS. -- Gum 16-25 p.c., resin (cambogic
acid) 66-80 p.c., volatile oil, phenol ester, methyl alcohol and other
alcohols, isovitinic and acetic acids, liquid with fruity odor resembling
an aldehyde or ketone, ash 1-3 p.c
Gum. -- Soluble in cold water like gum arabic
(arabin), but not identical with it, as it is not precipitated by lead
acetate, ferric chloride, sodium silicate, or sodium borate.
Resin. -- Soluble in ether and alcohol, forming
golden-yellow tinctures, also in alkaline solutions with red color, from
which it is precipitated unaltered by acids. It has acid characteristics,
hence sometimes called cambogic acid, and upon it the coloring matter and
medicinal properties depend; with salts of heavy metals forms precipitates
called cambogiates.
PREPARATIONS. -- 1. Pilulae Hydrargyri Chloridi
Mitis Compositae (Pilulae Catharticae Compositae, (1/4 g. (.016 Gm.).
Unoff. Prep.: Pilula Cambogiae Composita,
16 p.c. +, dose, gr. 4-8 (.26-.5 Gm.).
Poisoning: Similar to aloe, colocynth, elaterin,
etc.
PROPERTIES. -- Drastic, hydragogue cathartic; in
small repeated doses diuretic. Usually produces much griping, nausea
and vomiting when taken in full doses, so that generally it is combined
with other cathartics, as calomel, jalap, potassium bitartrate or carbonate,
etc.; it greatly irritates the alimentary canal, especially the small intestine,
when taken in excess, and gr. 60 (4 Gm.) have occasioned death; it augments
intestinal glands' secretion, but not of bile, and mostly passes in the
feces, but some is absorbed, causing yellow urine.
USES. -- Liver trouble from malaria; renal dropsy,
uremic conditions, congestion of the brain, tenifuge (combined usually
with tenicides), vermifuge, dropsy; very uncertain in veterinary practice.
Mostly used as pigment in water-color painting. The powder when rubbed
up with water shows strongly the "Brownian movement" under the microscope--infinitesimal
particles (gamboge, carmine, etc.) suspended in water or other liquid in
very delicate equilibrium, and sensitive to slightest change of temperature,
which causes movement--physical, not vital.
Allied Plants:
1. Several guttiferous plants of Southern India,
not restricted, however, to the Cambodia province, as is the official,
are almost identical with this latter and yield a similar juice: Garacinia
Morel'la (staminate flowers sessile), Ceylon, S. India; G. Travanco'rica,
Travancore; G. Picto'ria, Madras peninsula, etc.; G. Mangosta'na, Mango
Fruit, India, astringent; G. Purpu'rea (in'dica), India; the seed of this
are exposed to the sun and then boiled in water, when 10-20 p.c. of a fixed
oil (kokum-butter) is obtained.
Gaultheria
GAULTHERIA. GAULTHERIA.
Methylis Salicylas. Methyl Salicylate, U.S.P.
Gaultheria procumbens, Linne', or
Betula lenta, Linne'. An ester (compound ether) obtained
by distilling leaves of the former, or bark of the latter, and produced
synthetically.
Habitat. N. America, Newfoundland to
Georgia, Minnesota; cold damp woods (shade of evergreens); forests.
Syn. Wintergreen, Spring (Creeping,
Spicy, Aromatic) Wintergreen, Checker (Partridge) berry, Tea (Spice)
berry, Mountain Tea; Black (Cherry, Mahogany, Sweet, Spice) Birch,
Mountain Mahogany; Methyl, Salicyl., Oleum Gaultheriae, U.S.P. 1900,
Oil of Wintergreen; Oleum Betulae, U.S.P. 1900, Oil of Sweet Birch, Oil
of Teaberry; Fr. Salicylate de Methyle; Ger. Kunstliches Wintergrunol.
Gaul-the'ri-a. L. Dedicated by Kalm
to Dr. Gaulther, of Quebec.
Pro-cum'bens. L. Pro, forward, + cumbere,
to lie, lying down -- i.e., the reclining habit of the stem.
Bet'u-la. L. Fr. Celtic betu, the birch
-- i.e., its original name.
Len'ta. L. Lentus, soft, pliant, flexible
-- i.e., its stems and branches.
PLANTS. -- Gaultheria procumbens, stems slender,
creeping on or below the surface, branches ascending, leafy at summit,
5-15 Cm. (2-6') high; leaves obovate, alternate, evergreen, spicy, mucronate,
serrate; flowers, June-Sept., few, white, nodding, mostly single in the
axils; fruit (formed of calyx) bright red berries (capsules), 5-celled,
spicy, aromatic; Betula lenta--Betulaceae, tree 12-24 M. (40-80 degrees)
high, .6-1 M. (2-3 degrees) thick; bark dark brown, close, smooth, sweet
aromatic; leaves 7.5-10 Cm. (3-4') long, 2.5-5 Cm. (1-2') broad, ovate,
acuminate, serrate, petiolate; flowers, staminate (catkins) and pistillate;
bark not separable into layers, cambium when wounded in the spring, exudes
sweet, acid, edible juice; wood reddish, strong, compact.
CONSTITUENTS. -- Methyl Salicylate (Volatile oil),
resin, tannin 3-6 p.c., gaultherin, betulin.
Methylis Salicylas. Methyl Salicylate, C6H4(OH)CO2CH3
or CH3C7H5O3. -- While this
constitutes 98 p.c. of the commercial oils of gaultheria and betula, it
is obtained largely synthetically by distilling salicylic acid, or a salicylate,
with methyl alcohol and sulphuric acid (abstracting water as eliminated),
the methyl salicylate distilling over and floating on the surface -- HC7H5O3
+ CH3OH + H2SO4 = CH3C7H5O3
+ H2O + H2SO4. It is a colorless,
yellowish, reddish liquid, characteristic odor and taste of gaultheria,
soluble in 70 p.c. alcohol (7); with not more than slight cloudiness, slightly
in water, miscible with alcohol and glacial acetic acid; alcoholic solution
neutral, slightly acid, sp. gr. 1.183 (synthetic), 1.177 (from gaultheria
or betula); boils at 221 degrees C. (430 degrees F.); optically inactive
(synthetic and betula), slightly levorotatory (gaultheria); contains 98
p.c. of methyl salicylate. Tests: 1. Shake a drop with 5 cc.
of distilled water, + a drop of ferric chloride T.S.--deep violet color.
2. Agitated 1 cc. with potassium hydroxide T.S. 10 cc. -- clear, slightly
cloudy, colorless or faintly yellowish, without separation of oily drops
(abs. of other volatile oils, petroleum products). Impurities: Heavy
metals, volatile oils, petroleum products. The label must indicate
definitely its specific source. Should be kept cool, in well-stoppered,
amber-colored bottles. Dose, mj-10 (.06-.6 cc.).
PREPARATIONS. -- 1. Emulsum Olei Morrhuae, 2/5 p.c.
2. Fluidextractum Cascarae Sagradae Aromaticum, 1/50 p.c. 3. Syrupus
Sarsaparillae Compositus, 1/50 p.c. 4. Cataplasma Kaolini, N.F.,
1/5 p.c. 5. Dentifricium, N.F., 875/1000 p.c. 6. Inunctum Mentholis
Compositum, N.F., 10 p.c. 7. Liquor Antisepticus, N.F., 12/100 p.c.
8. Liquor Antisepticus Alkalinus, N.F., 1/20 p.c. 9. Liquor Ferri
Salicylatis, N.F., 1/5 p.c. 10. Liquor Pepsini Antisepticus, N.F.,
1/20 p.c. 11. Nebula Aromatica, N.F., ½ p.c. 12. Nebula
Mentholis Composita, N.F., ½ p.c. 13. Odontalgicum, N.F.,
45 p.c. 14. Petroxolinum Methylis Sallicylatis, N.F., 20 cc. in 100
cc. product. 15.Syrupus Trifolii Compositus, N.F., 1/50 p.c.
16. Trochisci Ulmi, N.F. 1/88 p.c.
Unoff. Preps.: Oil of Gaultheria (Br.), mj-10
(.06-.6 cc.). Spirit, 5 p.c., 3j-2 (4-8 cc.).
PROPERTIES AND USES. -- Similar to salicylic acid:
Antiseptic analgesic, stimulant, carminative, flavoring; muscular rheumatism,
lumbago, sciatica; locally applied upon lint over swollen joints, acute
articular rheumatism, tic douloureux, etc. Amount may be increased,
if no impairment of digestion, until full effect produced.
Poisoning: Large quantities produce drowsiness,
cerebral congestion, delirium, gastric irritability, vomiting, purging,
intestinal pain, rapid pulse, hot dry skin, difficult breathing; give diffusible
stimulants--ether, alcohol, ammonia, etc.
Gaultheria (Leaves), U.S.P. 1820-1880; Oleum
Gaultheriae, U.S.P. 1820-1900;Oleum Betulae (Volatile), U.S.P. 1890-1900.
Gelsemium
Gelse'mium semper'virens, Gelsemium, Yellow Jasmine
(Root), N.F.--The dried rhizome and roots with not more than 2 p.c. of
foreign organic matter; United States, Va. to Fla. Beautiful woody
climber; leaves persistent, evergreen, lanceolate, entire, flowers large,
yellow, fragrant, poisonous, corolla funnel-shaped; fruit brown, capsule.
Rhizome, cylindrical, in pieces 3-20 Cm. (1 1/5-8') long, 3-30 Mm. (1/8-1
1/5') thick, yellowish-brown, wrinkled, transverse fissures, few stem-scars
above, numerous roots beneath; fracture tough, splintery; bark thin; wood
radiate, excentric; odor slight; taste bitter. Powder, yellowish--tracheae,
few bast-fibers, lignified tracheids, starch grains, few calcium oxalate
monoclinic prisms, groups of stone cells; solvent: diluted alcohol; contains
gelsemine, gelseminine, gelsemic acid (beta-methyl-aesculetin) .3-.4 p.c.,
volatile oil .5 p.c., 2 resins 4 p.c., starch, gum, pectin. Nervine,
sedative, mydriatic, antispasmodic, antiperiodic; closely resembles hemlock
in action, and somewhat digitalis, aconite, veratrum viride, antimony;
rheumatism, neuralgia, intermittent and yellow fevers, headache, migraine,
asthma, chorea, epilepsy, nervous cough, mania. Poisoning:
Dim vision, projected eyeballs, dropping of upper eyelid and lower jaw,
difficult enunciation, labored breathing, convulsions (strychnine-like),
death--evacuants, tannin, cardiac stimiulants: ammonia, strychnine, atropine,
digitalis; external heat and friction. Dose, gr. 2-10 (.13-.6 Gm.);
1. Fluidextractum Gelsemii (80 p.c. alcohol), dose, mij-10 (.13-.6 cc.):
Preps.: 1. Elixir Sodii Salicylatis Compositum, 1.6 p.c.; 2. Tinctura Gelsemii,
10 p.c. (65 p.c. alcohol). Dose, mx-60 (.6- 4 cc.).
Gentiana
GENTIANA. GENTIAN, U.S.P.
Gentiana lutea, Linne'. The dried
rhizome and roots, yielding not less than 30 p.c. of water-soluble extractive.
Habitat. C. And S. Europe (France,
Austria, Germany, Switzerland, Portugal, England); mountainous districts.
Syn. Yellow Gentian Root, Pale Gentian,
Butter Root, Bitterwort, Felwort, Radix Gentianae Rubrae, Luteae
or Majoris; Gr. Gentianae Radix; Fr. Gentiane, Racine de Gentiane
(de Gentiane Jaune); Ger. Radix Gentianae, Enzianworzel, Bitterwurzel,
Rother (Gelber) Enzian.
Gen-ti-a'na. L. See etymology, page
487, of Gentianaceae.
Lu'te-a. L. Luteus, golden-yellow --
i.e., the flowers.
PLANT. -- Large perennial herb; stem thick, hollow
above, .6-1.3 M. (2-4 degrees) high, yellowish-green, underground portion
.6-1 M. (2-3 degrees) long, branched; leaves entire, 5-7-nerved, 15-30
Cm. (6-12') long, ovate, glabrous, yellowish-green; flowers June-Aug.,
numerous, cymes of 20 or more; corolla 5 Cm. (2') long, orange-yellow,
spotted, 6 segments; fruit 1-celled, ovate capsule, 3 Cm. (1 1/5') long,
many winged-seed. RHIZOME (root), in subcylindrical, sometimes branching
pieces, of variable length, 5-40 Mm. (1/5-1 3/5') thick, yellowish-brown,
rhizome annulate, roots longitudinally wrinkled; fracture short and uneven
when dry, tough and flexible when damp; internally yellowish-brown, bark
.5-2 Mm. (1/50-1/12') thick, separated from a spongy wood by a dark brown
cambium zone; odor strong, characteristic; taste slightly sweetish, strongly
and persistently bitter. POWDER, yellowish-brown -- parenchymatous
cells with fragments of scalariform or reticulate tracheae, few or no starch
grains and calcium oxalate crystals; no stone cells, bast- or wood-fibers.
Solvents: water; diluted alcohol. Dose, gr 5-30 (.3-2 Gm.).
ADULTERATIONS. -- RHIZOME: Through carelessness-rhizomes,
roots of allied species, especially G. Asclepia'dea (stone cells and prosenthymatous
tissue); aconite, belladonna, white hellebore, orris (none yellow internally),
Rumex alpi'nus (odor and taste distinct--bitter, astringent without gentian
aroma); POWDER: Ground pine-wood almond shells, olive stones, sack and
rope fibers, etc.
Commercial. -- Plant, remarkable for beauty
and size, was used by the Greeks and Arabians, and grows in the Alps, Apennines,
Pyrenees, Jura, Vosges, 900-1200 M. (3000-4000 degrees) elevation, along
with veratrum album, the leaves of both closely resembling. Rhizome
and roots are collected usually when in flower, washed, dried, and exported
from Germany, France (Marseillees) -- our chief supply. Austria imposes
a fine for collecting any less than 2 Cm. (4/5') thick at the crown--product
of plants 3 years old, which insures propagation through having produced
seed.
CONSTITUENTS. -- Gentiopicrin, Gentiin, gentiogenin,
C10H10O4, gentienin, C14H10O5,
gentianose, C10H66O31 (uncrystallizable
sugar) 14 p.c., resin, gum, pectin, fixed oil 6 p.c., yellow coloring matter,
identical with quercitrin, ash 6 p.c.
Gentiopicrin, C16H20O9.
-- Bitter glucoside, upon which activity depends, obtained by diluting
alcoholic extract with alcohol, extracting with equal weight of warm hydrous
ether, evaporating to get crystals that contain 1 p.c. gentiin, which can
be removed by recrystallizing from acetic ether + 2 p.c. of water; by hydrolysis
yields glucose and gentiogenin (white crystals).
Gentiin, C25H28O14.
-- Crystallizes from 60 p.c. hot alcohol in yellow needles, insoluble in
water, blackish-green with ferric chloride, heated with 4 p.c. of sulphuric
acid splits into glucose, xylose and gentienin.
PREPARATIONS. -- 1. Tinctura Gentianae Composita.
Compound Tincture of Gentian. (Syn., Tr. Gentian Co.; Fr. Teinture
de Gentiane composee; Ger. Zusammengesetzte Enziantinktur.)
Manufacture: 10 p.c. Similar to Tinctura
Veratri Viridis, page 104 -- using gentian 10 Gm., bitter orange
peel 4 Gm., cardamom seed 1 Gm., packing moderately; lst menstruum: glycerin
10 cc., alcohol 50, water 40, finishing with diluted alcohol q.s. 100 cc.
Dose, 3j-2 (4-8 cc.).
2. Extractum Gentianae, N.F. -- yield 30
p.c. (water). Dose, gr. 2-10 (.13-.6 Gm.).
Preps.: 1. Pilulae Antiperiodicae, N.F.,
q.s. 2. Pilulae Ferri, Quininae, Aloes et Nucis Vomicae, N.F., q.s.
3. Fluidextractum Gentianae, N.F. (diluted
alcohol). Dose, mv-50 (.3-2 cc.).
Preps.: 1. Elixir Gentianae, N.F.,
3.5 p.c. Dose 3j-2 (4-8 cc.).
Preps.: 1. Elixir Gentianae et Ferri,
N.F., 90 p.c. 2. Elixir Gentianae et Ferri Phosphatis, N.F.,
95 p.c. Dose, each, 3j-2 (4-8 cc.).
2. Elixir Gentianae Glycerinatum, N.F., 1
p.c. Dose, 3j-2 (4-8 cc.).
4. Infusum Gentianae Compositum, N.F., 3
p.c. Dose, 3ij-4 (8-15 cc.). 5. Tinctura Rhei et Gentianae,
N.F., 1 3/4 p.c. 6. Tinctura Amara, Bitter Stomach Drops, N.F., 6
p.c. + centaury 6, bitter orange peel 6, zedoary 2 (67 p.c. alcohol q.s.).
Dose, 3ss-1 (2-4 cc.). 7. Tinctura Antiperiodica, N.F., 1/5
p.c.
PROPERTIES. -- Tonic, bitter, increases appetite,
digestion (action local); large doses oppress stomach, irritate bowels,
nauseate, and cause vomiting.
USES. -- Dyspepsia, atonic gout, amenorrhea, hysteria,
scrofula, intermittents. G. Elliot'tii (Catesbae'i), Elliott's Gentian.--The
root, U.S.P. 1820--1870; United States, grassy swamps. Perennial
herb, 20-60 Cm. (8-24') high, rough; leaves 2.5-5 Cm. (1-2') long, lanceolate,
serrate; flowers Oct., blue, 4 Cm. (1 3/5') long; corolla 10 segments,
5 inner fringed; root resembles the official; constituents and uses similar;
in infusion, wine, tincture. G. purpu'rea (purplish flowers), G.
pannon'ica (dark purple flowers), and G. puncta'ta (yellow, purple-dotted
flowers); all grow along with official, and collected for it.
Geranium
Gera'anium macula'tum, Geranium, Cranesbill, N.F.
-- Geraniaceae. The dried rhizome with not more than 2 p.c. of foreign
organic matter; N. America, rich woods, thickets. Perennial, hairy
herb, .3-.6 M. (1-2 degrees) high; leaves palmately 5-7-lobed, each lobe
incised at apex, cuneate, hairy, pale green with paler spots; flowers large,
purplish, umbels; petals 5, entire; fruit long-beaked. Rhizome, cylindraceous,
2.5-10 Cm. (1-4') long, 3-15 Mm. (1/8-3/5') thick, somewhat branched, bent,
flattened, strongly tuberculated, root-scars, wrinkled, dark purple-brown,
internally light purple-brown; fracture short, non-fibrous, bark thin,
cambium distinct, irregular, wood-wedges, large central pith, few fibro-vascular
bundles; odorless; taste strongly astringent. Powder, purplish-brown
-- cortical and pith parenchyma, starch grains, calcium oxalate rosettes,
cork cells with brownish amorphous content, fragments bluish-black with
ammonio-ferric alum T.S.; tracheae, tracheids; solvents: alcohol, water;
contains tannin 10-28 p.c., gallic acid, resin, crystalline principle,
geranium-red, a phlobaphene formed from the tannin, ash 8 p.c. Astringent,
tonic; diarrhea, chronic dysentery, hemorrhages, gleet, leucorrhea, aphthae,
relaxed vagina, throat, uvula, rectum, indolent ulcers. Dose, gr.
15-60 (1-4 Gm.); 1. Fluidextractum Geranii (75 p.c. alcohol). Extract;Tincture;
Decoction, 5 p.c. (water or milk); "Eclectic" geranin.
G. Robertia'num. -- Europe; popular astringent
for hemorrhage, diuretic for gravel. Ero'dium (Geranium) moscha'tim,
Stork's-bill; diaphoretic. E. Cicuta'rium, Heron's-bill; diuretic
for dropsy.
Geum
Ge'um riva'le, Purple (Water) Avens. -- The
rhizome, U.S.P. 1820-1870; N. America. Perennial plant .3-.6 M. (1-2
degrees) high, stem purple; leaves 3-foliate or 3-lobed; flowers purplish-orange.
Rhizome 5-7.5 Cm. (2-3') long, 6 Mm. (1/4') thick, tuberculate, wrinkled,
brownish-red; bark thin, wood-wedges white, pith large; aromatic, astringent,
bitter; contains volatile oil, tannin, bitter principle. Astringent,
tonic; diarrhea, hemorrhage, leucorrhea, phthisis, scrofula, rheumatism,
intermittents, dyspepsia, menstrual derangements; decoction, infusion,
tincture. Dose, gr. 15-30 (1-2 Gm.).
Gillenia
Porteran'thus stipula'tus (Gille'nia stipula'cea),
Indian Physic, and P. Trifolia'tus (G. Trifolia'ta), American Ipecac.
-- The root, U.S.P. 1820-1870; United States; shrubs .6-1 M. (2-3 degrees)
high, stems reddish-brown, leaves trifoliate; leaflets 5-10 Cm. (2-4')
long, pubescent; flowers white, pink; root (rhizome) 12-25 Mm. (1/2-1')
thick, with thin bark and many fissured rootlets, 3-6 Mm. (1/8-1/4') thick,
bitter; contains gillenin, resin, tannin. Emetic (substitute for
ipecac), purgative, tonic; infusion, decoction, tincture; very popular
with North American Indians. Dose, emetic, gr. 15-30 (1-2 Gm.); tonic,
gr. 2-5 (.13-.3 Gm.).
Glaucium
Glau'cium Glaucium (lu'teum), Yellow Horned Poppy,
and G. cornicula'tum. -- Both are similar to chelidonium; contain yellow
juice and nearly identical alkaloids, hence used for about the same purposes.
Glycine
Glyc'ine (So'ja) his'pida, Soja Bean. -- Japan,
cultivated S. Asia; contains casein 40 p.c., fixed oil 15-20 p.c., dextrin
10, starch 5, cellulose 5, water 10, amylolytic ferment. Owing to
the beans containing so little starch they are ground into flour, and made
into bread for diabetic patients, in order to decrease sugar in the urine;
plant -- turned under as a nitrogenous fertilizer to land.
Glycyrrhiza
GLYCYRRHIZA. GLYCYRRHIZA, U.S.P.
Glycyrrhiza glabra, Linne' + var. typica,
Regel et Herder, glandulifera, Regal et Herder, or
other varieties yielding a yellow sweet wood. The dried rhizome and
roots with not more than 2.5 p.c. of acid-insoluble ash.
Habitat. S. Europe, W. Asia, Syria,
Persia, N. Africa; cult. In Russia, Spain, England, France, Germany,
United States, China; rich low-lands, river valleys.
Syn. Glycyrrh., Liquorice Root, Licorice,
Sweet Wood, Italian Juice Root (Wood), Spanish Juice Root, Radix
Glycyrrhizae Hispanicae; Br. Glycyrrhizae Radix; Fr. Reglisse, Bois
de Reglisae--doux, Racine douce; Ger. Radix Liquiritiae, Sussholz,
Spanisches Suseaholz, Lakritzenholz.
Glyc-yr-rhi'sa. L. Fr. Gr.... -- ...
, sweet, + ... , root -- i.e., its saccarine taste (Dioscorides).
Gla'bra. L. Glaber, smooth, hairless
-- i.e., pods, leaves smooth on both sides.
Glan-du-lif'e-ra. L. Glandula, a gland, +
ferre, to bear -- i.e., pods covered with thick glandular spines.
Ty'pi-ca. L. typicus, typical, representative--i.e.,
possessing the strongest characteristics of its group.
Lic'o-rice -- Liqu'uo-rice (lik'o-ris).
Fr. L. Liquiritia, corruption of glycyrrhiza.
PLANTS. -- Perennial herbs; stem .6-1.5 M. (2-5
degrees) high, several from the (crown) thick rhizome; leaves imparipinnate;
leaflets 4-7 pairs, ovate, entire, smooth, glutinous beneath, dark green;
flowers yellowish-white or purplish, pulse-shaped, racemes; fruit legume,
2.5 Gm. (1') long, brown, ovate, flat, 1-celled, 1-6 (kidney-shape) seeded;
G. glabra, var. glandulifera -- stem somewhat pubescent; leaves hairy,
glandular beneath; legumes glandular, prickly. RHIZOME (G. glabra,
var. typica): Spanish, nearly cylindrical, upper portion somewhat knotty,
usually in pieces 14-20 Cm. (6-8') long, 5-20 Mm. (1/5-4/5') thick, yellowish-brown
to dark brown, longitudinally wrinkled; thinner rhizomes often having prominent
alternate buds, thicker having distinct corky patches; fracture coarsely
fibrous; internally yellow, radiate; bark 1-3 Mm. (1/25-1/8') thick; wood
porous, in narrow wedges, rhizome with small pith -- none in roots; odor
distinctive; taste sweetish, slightly acrid -- bark; (G. glabra, var. glandulifera):
Russian, nearly cylindrical, somewhat tapering, sometimes split longitudinally,
15-30 Cm. (6-12') long, 1-5 Cm. (3/5-2') thick, pale yellow when deprived
of outer corky layer; fracture coarsely fibrous; internally pale yellow;
wood radially cleft; less sweet than preceding. POWDER, brownish-yellow
with reddish-brown cork cells (Spanish); pale yellow without reddish-brown
cork cells (Russian) -- numerous wood-fibers, bast-fibers, and starch grains,
.002-.02 Mm. (1/12500/1/1250') broad, tracheae, crystal-fibers with monoclinic
calcium oxalate prisms. Solvents: water, diluted alcohol. Dose,
gr. 15-60 (1-4 Gm.).
ADULTERATIONS. -- The one variety of the root with
the other, as they often are collected together; also the underground stem,
which resembles the root, but has a thin central pith; roots of allied
species (wood not yellow nor sweet), worm-eaten, decayed and discolored
pieces, fibrous roots (little sweetness).
Commercial. -- Plants, like lemon and orange,
do not thrive in cold lattitudes, becoming woody and less sweet, and while
formerly the wild grown, owing to hardy, persistent rapacious habit, supplied
the demand, now it is cultivated extensively by planting cuttings in rows,
4 feet (1.3 M.) apart. Roots are dug when sweetest, autumn of 4th
year -- preferably of plants that have not borne fruit, a process that
exhausts the sweetness of the sap, by removing the earth 2-3 feet (.6-1
M.) deep, the entire length of rows, thereby exposing subterranean portion
and allowing easy pulling up of whole plants, from which roots are taken,
cleaned, washed, trimmed, assorted, cut into suitable lengths, and marketed
via Alicante, Tortosa, Hamburg, in bundles, bales, bags. There are
two varieties: 1, Spanish (Italian, Turkish, Alicante, Tortosa -- G. Glabra,
var. typica), usually unpeeled and for a long time most esteemed, but as
bitterness and acridity reside in the bark it now constitutes only one-tenth
of that consumed; 2, Russian (G. glabra, var. glandulifera), usually peeled,
larger, richer in glycyrhizin and extractives, and in far greater demand.
The Calabrian is preferred by many, while the Italian and Sicilian are
consumed at home for making the extract.
CONSTITUENTS. -- Glycyrrhizin, C44H63O18N,
6-8 p.c., Glycyramarin, C36H57O13N (bitter
principle, mostly in the bark), sucrose, glucose, asparagin 2-4 p.c., fat
.8 p.c., volatile oil .03 p.c., gum, tannin, starch, resin, yellow coloring
matter, ash 5-7 p.c.
Glycyrrhixin -- This is combined with ammonia,
being called glycyrrhizate of ammonium or glycyrrhizic acid, C44H62O18N.NH4.
It is a tribasic acid (glucoside) obtained from cold infusion by coagulating
albumin with heat, filtering, precipitating with sulphuric acid, washing
precipitate with water, dissolving it in alcohol to which a little ether
has been added (or in very weak ammonia water, 1 to 10), filtering, evaporating;
it is very soluble in water, sparingly in alcohol, ether, when boiled with
diluted sulphuric acid (by hydrolysis) splits into parasaccharic acid (glucose),
C6H10O8, and bitter resinous glycyrrhetin,
C32Y47O4N.
PREPARATIONS. -- 1. Extractum Glycyrrhizae.
Extract of Glycyrrhiza. (Syn., Ext. Glycyrrh., Extract of Licorice,
Extractum liquiritiae, Licorice; Fr. Suc (jus) de Reglisse, Sucre noir;
Ger. Succus Liquritiae, Sussholzsaft, Lakritz, Lakritzensaft.)
Manufacture: Evaporate decoction to proper
consistence, pulverize or mold. This is the commercial extract, in
flattened, cylindrical masses or rolls, 15-18 Cm. (6-7') long, 15-30 Mm.
(3/5-1 1/5') thick, glossy black, brittle, sharp, smooth conchoidal fracture;
characteristic, sweet taste: yield 26-32 p.c., containing glycyrrhizin
10-24 p.c.; at least 60 p.c. soluble in cold water; powder brown; ash 8
p.c. Dose, ad libitum.
Preps.: 1. Trochisci Ammonii Chloridi,
3 gr. (.2 Gm.). 2. Pilulae Ferri Iodidi, N.F., 1/6 gr. (.01
Gm.).
2. Extractum Glycyrrhizae Purum.
Pure Extract of Glycyrrhiza. (Syn., Ext. Glycyrrh. Pur., Pure Extract
of Licorice Root; Br. Extractum Glycyrrhizae, Extractum Glycyrrhizae Depuratum;
Fr. Extrait de Reglisse (pur); Ger. Succus Liquiritiae depuratus, Gereinigter
Sussholzsaft.)
Manufacture: Macerate, percolate, in metallic
percolator, 100 Gm. with boiling water until exhausted; promptly evaporate
to a pilular consistency; yield 16-25 p.c. Dose, ad libitum.
Prep.: 1. Fluidextractum Cascarae Sagradae
Aromaticum, 4 p.c.
3. Fluidextractum Glycyrrhizae. Fluidextract
of Glycyrrhiza. (Syn., Fldext. Glycyrrh, Fluidextract of Licorice,
Fluid Extract of Glycyrrhiza; Br. Extractum Glycyrrhizae Liquidum; Fr.
Extrait fluide de Reglisse; Ger. Sussholzfluidextrakt.)
Manufacture: Macerate 100 Gm. + 500 cc. boiling
water 2 hours, pack in a tinned or enameled metallic percolator, exhaust
with boiling water, promptly evaporate to 75 cc., cool, add alcohol 25
cc., mix, allow to stand 7 days in a stoppered container, decant clear
liquid, filter remainder, wash residue with mixture alcohol 1, water 3,
q.s. 100 cc. Dose, mxv-60 (1-4 cc.).
Preps.: 1. Elixir Glycyrrhizae.
Elixir of Glycyrrhiza. (Syn., Elix. Glycyrrh., Elixir Adjuvans, Elixir
of Licorice, Flavoring Elixir; F. Elixir de Reglisse -- adjuvant; Ger.
Gewurzhaftes Lakritzenelixir.)
Manufacture: Mix fluidextract of glycyrrhize
12.5 cc. With aromatic elixir 87.5 cc., filter. Dose. ad libitum;
as a flavoring vehicle.
2. Mistura Glycyrrhizae Composita.
Compound Mixture of Glycyrrhiza. (Syn., Mist. Glycyrrh. Co., Brown
Mixture; Fr. Mixture de Reglisse; Ger. Lakritzenmixtur.)
Manufacture: Dilute fluidextract of glycyrrhiza
12 cc. with glycerin 12, water 50, add antimony
and potassium tartrate .024 Gm., dissolved in hot water 1.2 cc., then camphorated
tincture of opium 12, spirit of nitrous ether 3, and water q.s. 100 cc.,
mix. Dose, 3ss-4 (2-15 cc.).
3. Syrupus Sarsaparillae Compositus,
1.5 p.c. 4. Elixir Glycyrrhizae Aquosum, N.F., 15 p.c.: Prep.:
1. Elixir Cascarae Sagradae, N.F., 50 p.c. 5. Elixir Tarazaci Compositum,
N.F., 6 p.c.
4. Pulvis Glycyrrhizae Compositus.
Compound Powder of Glycyrrhiza. (Syn., Pulv. Glycyrrh. Co., Compound
Licorice Powder; Fr. Poudre pectorale de Reglisse composee; Ger. Pulvis
Liquiritiae compositus (Pectoralis Kurellae), Brustpulver.)
Manufacture: Mix oil of fennel .4 Gm. with
sucrose 50 Gm., add glycyrrhiza 23.6, senna 18, washed sulphur 8; mix thoroughly,
pass through No. 80 sieve. It is greenish-yellow, fennel-like odor
-- fragments of glycyrrhiza with yellow fibers, crystal-fibers, large tracheae,
starch grains, .002-.02 Mm. (1/12500-1/1250') broad; fragments of senna
with non-glandular hairs, epidermis, stomata with 2 neighboring cells,
crystal-fibers. Tests: 1. Moisten .1 Gm. with alcohol 2 cc, + water
10 cc., boil, cool, filter; filtrate -- pale yellowish-brown; + 1 drop
of potassium hydroxide T.S.--changes at once to yellowish-red; should be
free from hydrogen sulphide odor. Dose, 3ss-2 (2-8 Gm.).
5. Massa Hydrargyri, 10 p.c.
6. Fluidglyceratum glycyrrhiae, N.F.,
100 p.c.
Preps.: 1. Syrupus Glycyrrhizae, N.F.,
25 p.c., + syrup q.s. 100; or macerate root (20) in water (100) +
ammonia water (10) for 12 hours, filter, add syrup q.s. 100 parts; or mix
fluidextract (2) with syrup (8). Dose, ad libitum; mostly for flavoring;
2. Elixir Bromidorum Quinque, N.F., 8 p.c.; 3. Elixir Guaranae et
Apii, N.F., 3 p.c.
7. Fluidextractum Sarsaparillae Compositum, N.F.
12 p.c. 8. Fluidextractum Trifolii Compositum, N.F., 21.5 p.c.
9. Pilulae Ferri Iodidi, N.F., 2/3 gr. (.045 Gm.). 10. Pilueae Laxativae
Compositae, N.F., 2/3 gr. (.045 Gm.). 11. Species Pectorales, N.F.,
15 p.c. 12. Tinctura Aloes, N.F., 20 p.c. 13. Tinctura Aloes
et Myrrhae, N.F., 10 p.c. 14. Tinctura Rhei Dulcis, N.F., 4 p.c.
Unoff. Preps.: Ammoniated Glycyrrhizin,
gr. 5-15 (.3-1 Gm.). Decoction, Infusion, each, 5 p.c.
PROPERTIES. -- Demulcent, expectorant, laxative;
locally--slight stimulant. Increases, when chewed, the flow of saliva
and mucus, which secretions are emollient to the throat.
USES. -- Febrile catarrhal conditions, bronchitis,
bowel and urinary affections; here should be prepared with flaxseed, rice,
barley, or gum water. In pharmacy used to mask taste of aloe, ammonium
chloride, bitter sulphates, colocynth, guaiacum, hyoscyamus, mezereum,
senega, senna, quinine, turpentine, etc. Mechanically as an excipient
and dryer in pills, troches, etc.
Allied Plants:
1. Glycyrrhiza echina-ta. -- Europe, Hungary,
S. Russia; flowers in globular heads, pod ovoid with long spines.
G. Lepido'ta; United States (Mo., Minn.).
2. A'brus precato'rius, Indian (Wild) Licorice,
Jequirity, India, Brazil. -- Seed used as standard weight, and for criminal
poisoning, although inert when taken whole; contain abrin, having the action
of snake-venom, being cardiac depressant; root contains glycyrrhizin, but
is a poor substitute for glygyrrhiza.
3. Ono'nis spino'sa, Rest-harrow, Europe.
-- Root .6 M. (2 degrees) long, 12 Mm. (1/2') thick; odor and taste similar
to official glycyrrhiza.
4. Ar'achis hypogae'a, Peanut, Groundnut.
-- Tropical America, cult. United States. Small succulent plant,
yielding abundant subterranean seed, which are edible, popular and contains
fixed oil 45 p.c. suitable for replacing sesame or olive oil.
Gnaphallium
Gnapha'lium obtusifo'lium (polyceph'alum), Common,
Sweet, or Fragrant Life Everlasting. -- Annual erect herb, .3-1 M.
(1-3 degrees) high, woolly, fragrant; leaves lanceolate, undulate, sessile,
flowers in heads, clustered at summit of corymbose branches, obovate, whitish
involucre, yellow, tubular, odor pleasant, bitter; contains volatile oil
and bitter principle. Used for diarrhea, hemorrhages, externally
in fomentation and as a vulnerary to bruises, ulcers, etc. Dose,
3ss-1 (2-4 Gm.).
Gossypium
GOSSYPIUM. COTTON.
1. GOSSYPIUM PURIFICATUM. Purified
Cotton, U.S.P.
2. OLEUM GOSSYPII SEMINIS
Cottonseed oil, U.S.P.
Gossypium herbaceum, Linne', or other
species. 1. The hairs of the seed of cultivated varieties,
freed from adhering impurities and linters, and deprived of fatty matter.
2. The refined fixed oil from the seeds of cultivated varieties.
Habitat. C. Asia, India, China, Arabia,
N. E. Africa, Egypt; cultivated in United States, W. Indies, C. And
S. America, N. Africa, Australia, Spain.
Syn.1. Gossyp. Purif., Absorbent Cotton,
Gossypium, Cotton, Cotton Wool; Fr. Coton; Ger. Gossypium depuratum,
Gereinigte Baumwolle. 2. Ol. Gossyp. Sem., Cotton Seed oil;
Fr. Huile (de Coton) de Semences de Cotonnier; Ger. Baumwollsamenol.
Gos-syp-i-um. L. fr. Ar. Goz, Gothn,
a soft, milky substance -- i.e., the hairs of the seeds.
Her-ba'ce-um. L. Herbaceus, grassy,
herby -- i.e., the plant habit.
PLANT. -- Small biennial or triennial shrub; stem
branching, 1.5-3 M. (5-10 degrees) high, more or less woody; leaves hoary,
palmately 3-5-lobed; flowers large, 5-7.5 Cm. (2-3') long and wide, yellow,
purple spot near the claw; fruit capsule or boll 4-5 Cm. (1 3/5-2') long,
3-5-celled, opening by as many valves when ripe, revealing loose, white
tuft of long, slender hair that surrounds each one of the numerous seeds.
HAIRS OF THE SEED, in white soft fine filaments, 12-37.5 Mm. (1/2-1 1/2')
long; under microscope hollow, flattened, twisted bands, spirally striate,
slightly thickened edges; odorless; almost tasteless; insoluble in ordinary
solvents. Tests: 1. Compress in the hand, throw upon cold water --
readily absorbs latter and sinks. 2. Incinerate 5 Gm. -- ash .2 p.c.
3. Thoroughly saturate 10 Gm. with water 100 cc., with glass rod press
out 2 separate portions, 25 cc. each; first portion, + 3 drops of phenolphthalein
T.S.--no pink color (abs. of alkali); second portion, + 1 drop of methyl
orange T.S. -- no pink color (abs. of acid). 4. Exhaust 10 Gm. With
ether q.s. 200 cc., evaporate to dryness-residue not over .6 p.c. (abs.
of fatty matter). 5. Extract 10 Gm. with alcohol q.s. 50 cc.; observed
downward through a column 20 Cm. I depth -- may show yellowish color, but
no blue or green (abs. of dyes). Impurities: Alkali, acid, fatty
matter, dyes, water-soluble substances. Solvent: Ammoniated cupric
oxide T.S. OIL OF THE SEEDS, a pale yellow, oily liquid, odorless,
nearly odorless, bland taste, slightly soluble in alcohol; miscible with
ether, chloroform, petroleum benzin, carbon disulphide, sp. gr. 0.9l8;
on cooling below 12 degrees C. (54 degrees F.) particles of solid fat separate,
and at -5 degrees C. (23 degrees F.) nearly or quite a solid. Tests:
1. Oil and carbon disulphide equal volumes + sulphuric acid (sp gr.
1.6-1.7) -- reddish-brown color rapidly produced. 2. Mix 2 cc. with
2 cc. of a mixture of equal vols. amyl alcohol and a 1 p.c. solution of
precipitated sulphur in carbon disulphide, and immerse to one-third depth
in boiling saturated aqueous solution of sodium chloride -- red color in
10-15 minutes. Dose, 3ij-8 (8-30 cc.).
SUBSTITUTIONS. -- I. HAIRS: Boehme'ria ni'vea, fiber
may be used for cotton, lint, etc. II. OIL: 1, Brazil or Para
Nut Oil; nuts 2.5-5 Cm. (1-2') long, 3-edged, brownish-gray kernel, white,
almond taste; yield 60 p.c. oil; 2, Oleum Fagi, Beech Oil, from fruit of
Fa'gus sylvat'ica, kernels yield 22 p.c. oil; yellow, sp. gr. 0.922, congeals
at -17.5 degrees C. (0 degree F.).
Commercial. -- Cotton was known to the Arabians,
Egyptians, and Chinese in the 10th century, and was carried to Spain by
the Moors in the 16th century. The ancient Egyptians possibly were
unacquainted with it, as their mummy fibers are all linen, and no seeds
or paintings of plants are found in the tombs. However, in Peru mummy
clothing from earliest date contain, cotton, consequently here may be its
original habitat. Many species now give similar products, but our
own is thought to be from G. Barbadense, Barbados Islans, W. Indies.
Chapman refers long-staple or Sea Island cotton, which we cultivate, to
G. Ni'grum, and short-staple or Upland cotton to G. Al'bum. The hairs
are removed by hand or mill (cotton gin) from the seeds, and owing to the
latter containing fixed oil, 15-20 p.c., a portion of it becomes absorbed
by the attached fiber and must be eliminated before adapted for general
use. Purification is effected by boiling carded cotton in 5 p.c.
solution of potassium or sodium hydroxide, washing with water to remove
soap, expressing, adding 5 p.c. solution of chlorinated lime, allowing
to stand half an hour, washing, expressing, adding acidulated (HCl 5 p.c.)
water, washing, expressing -- a process that may be repeated if necessary,
removing 7-10 p.c. of weight, chieflyfat. The oil is obtained by
cracking off testa, grinding and expressing kernels; at first it is thick,
reddish-brown, turbid from albumen and mucilage, which mostly subside on
standing, yielding orange-colored clarified oil; when this is treated with
boiling water or superheated steam albuminoids are coagulated, giving lighter
colored refined oil, which upon being bleached (agitated with alkaline
solution and heated) yields winter-bleached oil; the loss in refining is
5-10 p.c., and as such is official. It is exported extensively for
olive oil adulteration, for which demand a line of tanked steamers ply
regularly between New Orleans and Europe, each having a capacity of 500,000-1,000,000
gallons; 12,000-20,000 barrels (1894-3788 KI.).
CONSTITUENTS. -- I. HAIRS: Cellulose (C6H10O5)x,
inorganics 1.5 p.c., fixed oil 7-10 p.c. II. OIL: Olein, palmitin,
linolein, glyceride of linoleic acid, and non-saponifiable yellow coloring
matter.
PREPARATIONS. -- I. HAIRS: 1. Pyroxylinum.
Pyroxylin. (Syn., Pyroxylin, Soluble Gun Cotton, Colloxylin, Collodion
Cotton, Lana Collodii; Fr. Fulmicoton soluble; Ger. Kollodiumwolle.)
Manufacture: Macerate purified cotton in
a cooled mixture of 14 vols. of nitric acid and 22 vols. of sulphuric acid
until the cotton is soluble in a mixture of 1 vol. of alcohol and 3 vols.
of ether, remove adhering acid by washing first with cold, then boiling
water, dry in small portions at 60 degrees C. (140 degrees F.). It
is a yellowish-white matted mass of filaments, resembling raw cotton in
appearance, harsh to the touch, exceedingly inflammable, burning, when
unconfined, very rapidly with luminous flame, less explosive than cellulose
hexanitrate; kept in well-closed bottles exposed to light, decomposes with
evolution of nitrous vapors, and carbonaceous residue; consists chiefly
of cellulose tetranitrate, C12H16O6(NO3)4.
Tests. 1. Soluble slowly but completely in 25 parts of a mixture
of 1 vol. Of alcohol and 3 vols. Of ether; soluble in acetone, glacial
acetic acid, and precipitated from these solutions on the addition of water.
2. Saturate .5 Gm. With alcohol in a dish in cold water, ignite from top;
when combustion complete, heat dish to redness -- ash .3 p.c. 3.
Stir 1 Gm. + water 20 cc. For 10 minutes, filter -- filtrate shows no acid
reaction; 10 cc. Evaporated to dryness on water-bath -- residue not more
than .0015 Gm. (Abs. Of soluble substances). Should be kept dark,
dry, in cartons packed loosely.
Prep.: 1. Collodion. Collodion.
(Syn., Collod.; Fr. Collodion; Ger. Collodium, Kollodium.)
Manufacture: Shake in a tared bottle collodion
95 Gm., castor oil 3, camphor 2, until latter dissolved. Should be
kept cool, remote from fire, in well-closed containers.
Preps.: 1. Collodium Bituminis
Sulphonati, N.F., 90 p.c. 2. Collodium Salicylicum Compositum, N.F.,
90 p.c. 3. Collodium Stypticum, N.F., 90 p.c.; each should be kept
cool, in tightly-stoppered bottles.
2. Gossypium Stypticum, N.F. -- macerate
100 Gm. for 1 hour in solution of ferric chloride 80 cc., glycerin 16,
water 225, press until it weighs 300 Gm., dry; keep in well-closed glass
containers. II. OIL: 1. Linimentum Camphorae, 80 p.c. 2. Ampullae
Camphorae, N.F., q.s. 3. Unguentum Picis Compositum, N.F., 34 p.c.
Unoff. Preps.: I. HAIRS: Medicated Cottons
(borated, benzoinated, chlorinated, phenolated (carbolated), salicylated,
iodoform, mercuric (bi)chloride, hemostatic, etc.); Iodine Collodion, 5
p.c.; Iodoform Collodion, 5 p.c., Croton Oil Collodion, 10 p.c. II.
SEED: Cottonseed Tea (mucilaginous drink for dysentery, diarrhea, etc.)
PROPERTIES. -- I. HAIRS: Protective. II. OIL:
Demulcent, nutrient.
USES. -- I. HAIRS: Dressing in burns, scalds, erysipilas,
blisters, surgical wounds; prevents entrance of organic germs that cause
suppuration and septic disease. Cotton batting maintains local heat
in pneumonia, rheumatism, and may be made into pessaries. II. OIL:
Like olive and almond oils in pharmacy, liniments, etc., in culinary use
for lard; to adulterate olive oil, in preparing woollen cloth, morocco
leather, lubricating machinery, etc.
Derivative Product:
L. Gossypii (Radicis) Cortex, Cotton Root
Bark, N.F. -- The recently gathered air-dried bark of the root of one
or more cultivated varieties with not more than 5 p.c. of wood or other
foreign organic matter. Root-bark, in flexible bands, quilled pieces,
up to 30 Cm. (12') in length, 1 Mm. (1/25') thick, orange-brown, smooth,
usually finely wrinkled, fissured, roughened from exfoliation of corky
layers, fuzzy; inner surface light brown, striate; fracture tough, fibrous,
separable into fibrous layers; odor slight, taste slightly acrid.
Powder, brownish -- numerous bast-fibers, cortical parenchyma, starch grains,
secretory reservoirs, medullary ray cells, calcium oxalate rosette crystals;
solvents: diluted alcohol, boiling water; contains resin (acrid, colorless,
soluble in water, becoming red on exposure and insoluble) 8 p.c., fixed
oil, tannin, starch, ash 7 p.c. Emmenagogue, oxytocic, uterine hemostatic,
similar to ergot, but less reliable; dysmenorrhea, amenorrhea, uterine
tumors and hemorrhages -- popular among negroes (who brought it from Africa)
in Southern States for inducing abortion. Dose, 3ss-1 (2-4 Gm.);
1. Fluidextractum Gossypii Corticis (alcohol), dose, 3ss-1 (2-4 cc.).
Decoction -- 3iv (120 Gm.) + water Oij (900 cc.), evaporated to Oj (450
cc.), 3ij (60 cc.), every half hour. G. Barbaden'se, G. Arbo'reum,
G, religio'sum (fibers yellow), etc., furnish products which may be used
similarly to the official.
Grindelia
Grindelia campo'rum,or G. Cuneifo'lia, G. Squarro'sa,
Grindelia, Gum-plant, N.F. -- The dried leaves and flowering tops with
not more than 10 p.c. of stems over 2 Mm. (1/12') thick, or 2 p.c. of other
foreign organic matter; N. America, west of Rocky mountains. Plants
-- small perennial, woody herbs, .3-1 M. (1-3 degrees) high, bushy; stems
and branches cylindrical, yellowish, pinkish, alternate leaf-scars and
basal portions of leaves, sometimes flexuous and coated with resin, terminating
in resinous flower-heads; leaves usually separate and broken, oblong, oblong-spatulate,
1-7 Cm. (2/5-3') long, sessile, or amplexicaul, serrate, yellowish-green,
resinous, coriaceous, brittle; flower-heads 5-20 Mm. (1/5-4/5') broad,
urceolate, resinous, involucre bracts numerous, imbricated with recurved
tips; ray-florets yellowish-brown, ligulate and pistillate; disk-florets
yellow, perfect, pappus of 2-3 linear arns; disk achenes ovoid, oblong,
angled, irregular simmit; odor balsamic; taste aromatic, bitter, resinous.
Powder, yellowish-brown -- numerous fibrous fragments bearing tracheae
with thickenings or pores, lignified wood-fibers, pith cells with protoplasm
bearing spheroidal granules; fragments of leaf epidermis with polygonal
areas, chloroplastids, glandular hairs, spherical pollen grains; solvent:
alcohol; contains resin (activity), bitter principle 1-2 p.c., volatile
oil, grindeline, fixed oil, tannin 1.5 p.c., ash 7-8 p.c. Cardiac
tonic (slows heart action), expectorant, antispasmodic, diuretic; asthma,
bronchitis, whooping-cough, catarrh of bladder and uterus, poisoning by
rhus toxicodendron -- in solution or poultice. Dose, gr. 15-60 (1-4
Gm.); 1. Fluidextractum Grindeliae (75 p.c. alcohol), dose, mxv-60
(1-4 cc.). Extract, gr. 5-15 (.3-1 Gm.). Infusion. Tincture.
G. Glutino'sum, stem often purplish tomentose, and G. Hirsu'tula, W. United
States, being very similar are often collected and mixed with commercial
drug.
Guaiacum
Guai'acum officina'le or G. Sanc'tum, Guaiac,
Guaiac Resin, N.F. -- Zygophyllaceae. The resin of the wood,
yielding not more than 15 p.c. of residue insoluble in alcohol; W. Indies,
S. America. Small trees 6-9 M. (20-30 degrees) high, stem-bark ash-gray,
striated, spotted; leaves paripinnte, yoked in pairs, evergreen; leaflets
2.5-4 Cm. (1-1 2/5') long; flowers large, blue; fruit 2-5-celled capsule;
seeds black, red. Wood (Lignum Vitae): sap yellowish, heart brownish,
heavier than water, sp. Gr. 1.30, hard, dense, touch, resinous, with heat--emitting
balsamic odor; taste slightly acrid; in shop as raspings. Resin:
in irregular fragments, large masses, tears, brown--greenish gray-brown
on exposure; fracture with glassy luster, thin pieces translucent, reddish
to yellowish-brown. Powder, grayish, becoming green on exposure;
odor balsamic; taste slightly acrid; soluble in alcohol, ether, chloroform,
creosote, solutions of alkalies, chloral hydrate T.S., sparingly in carbon
disulphide, benzene; alcoholic solution with excess of chlorine water or
tincture ferric chloride--blue, changing quickly to green; solvents: alsohol,
acetone, chloroform; contains quaiaretic acid, guaiaconic acid (alpha-resin)
50-70 p.c., guaiac beta-resin 10 p.c., gum 4-9 p.c., guaiacic acid, guaiac-yellow,
by dry distillation get guaiacol. Alterative, diaphoretic, expectorant,
stimulant, antiseptic; rheumatism, gout, lumbago, syphilis, scrofula, amenorrhea,
dysmenorrhea, diphtheria. Dose, gr. 5-30 (.3-2 Gm.); 1. Tinctura
Guaiaci, 20 p.c. (alcohol), dose mv-60 (.3-4 cc.); 2. Tinctura Guaiaci
Ammoniata, 20 p.c. (sp. ammon. arom.), dose, mv-30 (.3-2 cc.): Prep.: 1.
Gargarisma Guaiaci Compositum, 10 p.c. + tr. cinch. co. 10, honey 20, pot.
chloras 4, +; 3. Tinctura Guaiaci Composita, Dewees' Tincture
of Guaiac, 12.5 p.c., + pot. carb. .6, pimenta 3.2 (diluted alcohol), dose,
mv-60 (.3-4 cc.). Mixture (Br.), 2.5 p.c., 3iv-8 (15-30 cc.).
Lozenge (Br.), 3 gr. (.2 Gm.), Syrup. G. Angustifo'lium; S. Texas,
Mexico. Wood hard, heavy, splitting irregularly, yellowish-brown;
sometimes substituted for the preceding.
Guarea
Gua'rea (Sycocar'pus) Rus'byi, Cocillana, N.F.
-- Meliaceae. The dried bark with not more than 5 p.c. of wood or
other foreign organic matter; Bolivia -- river-bottoms. Tree resembles
a large apple tree. Bark, in flat, curved pieces, variable length
and width, up to 2 Cm. (4/5') in thickness, externally fissured, gray-brown,
ashy gray from lichens, orange-brown where cork removed, inner surface
brownish, longitudinally striate; inner bark thicker than outer; fracture
coarsely splintery-fibrous, soft; odor characteristic; taste slightly astringent,
peculiar, slightly nauseous. Powder, light brown -- lignified fibers,
crystal-fibers, calcium oxalate prisms, medullary ray cells with brownish
contents or starch grains, abundant stone cells, fragments of cork tissue;
solvent: 75 p.c. alcohol; contains rusbyine, resins (2) alkaloid, fat,
tannin, ash 10 p.c. (superior to ipecac), laxative, emetic, bronchitis,
bronchial pneumonia, phthisis. Dose, gr. 5-20 (.3-1.3 Gm.); 1. Fluidextractum
Cocillanae. Syrup, Elixir, each 10 p.c., dose, 3j-2 (4-8 cc.).
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